3' 5-Methyl dC
Return to Modified Bases Modifications5-Methyl deoxyCytidine when substituted for dC will increase the Tm by as much as 0.5°C per insertion. In addition, the presence of 5-Methyl dC in CpG motifs can prevent or limit unwanted immune responses that otherwise occur if oligos are administered in vivo, which is of particular importance in antisense applications.
Scientific Details
| MW: | 303.2 |
| Mod Code: | /3Me-dC/ |
Pricing Details
| Product | Pricing | Order |
|---|---|---|
| 100 nmole DNA Oligo | $98.00 USD | Add To Order |
| 250 nmole DNA Oligo | $120.00 USD | Add To Order |
| 1 umole DNA Oligo | $180.00 USD | Add To Order |
| 2 µmole DNA Oligo | $221.00 USD | Add To Order |
| 5 umole DNA Oligo | $391.00 USD | Add To Order |
| 10 umole DNA Oligo | $730.00 USD | Add To Order |
| 100 nmole RNA Oligo | $98.00 USD | Add To Order |
| 250 nmole RNA Oligo | $120.00 USD | Add To Order |
| 1 umole RNA Oligo | $180.00 USD | Add To Order |
| 5 umole RNA Oligo | $391.00 USD | Add To Order |
| 10 umole RNA Oligo | $730.00 USD | Add To Order |
Structure